Rosie O’Donnell is turning heads!

Over the years, she’s shared her journey with honesty and vulnerability.

More recently, Rosie’s revealing she’s been using Mounjaro, the type 2 diabetes medication now gaining traction as a powerful tool for weight loss.

Now she’s sharing how she is feeling about her new figure.

Rosie’s Weight Loss Wonder

Over the weekend, Rosie took to IG to share a new weight loss photo on stage.

She captioned a recent photo, “I can’t believe this is me now,” adding, ” “#mounjaro,”#weightloss” and “#bodydismorphia.”

A Health Crisis That Changed Everything

In 2012, Rosie suffered a massive heart attack—what doctors called a “widow-maker.”

That moment forced her to take a hard look at her lifestyle, weight, and long-term health.

Gastric Sleeve Surgery: The First Step

Rosie’s gastric sleeve procedure involved reducing the size of her stomach, limiting the amount of food she could eat and helping her feel full faster. It was a turning point, and she went on to lose over 60 pounds in the months following surgery.

She began making health-conscious lifestyle changes, including eating more whole foods, moving her body daily, and taking her mental health seriously.

The Mounjaro Revelation: Rosie Goes Public

In January 2023, Rosie O’Donnell first revealed she was using Mounjaro (tirzepatide)—a prescription medication originally developed for type 2 diabetes but now widely prescribed off-label for weight loss.

Mounjaro, which works by mimicking two key hormones that regulate blood sugar and appetite, has shown remarkable results in many users, including Rosie.

What Is Mounjaro?

• FDA-approved for type 2 diabetes
• Promotes weight loss by reducing hunger and improving insulin sensitivity
• Taken as a weekly injection
• Similar to Ozempic and Wegovy, but may lead to greater results for some

Rosie’s Results with Mounjaro

Since adding Mounjaro to her routine, Rosie has seen continued weight loss and stabilization. She’s also reported having:

• More energy
• Fewer food cravings
• Better blood sugar control
• A renewed sense of confidence

She has remained transparent about her use of the medication, helping break down stigma around pharmaceutical support for obesity.

Diet, Exercise, and Mental Health Still Matter

While Mounjaro has helped Rosie accelerate her progress, she emphasizes that it’s not a magic pill. Her routine still includes:

• Healthy eating with lean proteins, vegetables, and fewer processed carbs
• Regular movement, including walking and low-impact exercises
• Mental health care, including therapy and mindfulness practices

Why Rosie’s Story Is So Powerful

Rosie O’Donnell’s weight loss journey is about resilience, self-awareness, and taking control. From a life-threatening heart attack, to surgery, to embracing medical advances like Mounjaro—she has never stopped evolving.

She continues to advocate for:

• Heart disease awareness in women
• Body positivity
• Mental health care
• Weight stigma reform, especially around medications like Mounjaro

FAQs About Rosie O’Donnell’s Weight Loss

What weight loss surgery did Rosie O’Donnell have?

Gastric sleeve surgery in 2013.

Is Rosie O’Donnell on Mounjaro?

Yes. She began using Mounjaro in early 2023 and has publicly shared her positive results.

How much weight has she lost total?

Rosie has lost over 60 pounds post-surgery, with further weight loss aided by Mounjaro and healthy living.

Does Rosie still exercise and follow a diet?

Yes. Rosie continues to emphasize nutrition, fitness, and mental wellness.